Optimizing nanoparticles for commercial applications

Apr. 26, 2013 ? Nanoparticles are used in many commercial products catalysts to cosmetics. A review published today in the Science and Technology of Advanced Materials by researchers in Sweden and Spain describes recent work on the 3 main nanoparticles used in photocatalytic, UV-blocking and sunscreens.

Nanoparticles are currently used in commercial products ranging from catalysts, polishing media and magnetic fluids to cosmetics and sunscreens. A new review by researchers in Sweden and Spain describes recent work to optimize the synthesis, dispersion and surface functionalization of titania, zinc oxide and ceria -- the three main nanoparticles used in photocatalytic, UV-blocking and sunscreen applications.

With the commercial success of self-cleaning glass in the window frames of high-rise buildings, there is growing interest in applying photocatalytic, self-cleaning titania coatings on building facades and other construction materials. These coatings not only can keep building surfaces clean but also reduce concentrations of harmful airborne pollutants. The antibacterial properties of photocatalytic coatings also offer a means of managing persistent bacteria, mainly in hospitals.

Transparent UV-absorbing or UV-blocking coatings currently have two main applications: as a UV-protecting lacquer for wooden surfaces, and as a UV-barrier coating deposited on the surface of polymer-based products or devices to slow down their deterioration.

Published in the journal, Science and Technology of Advanced Materials, this study describes the structural and chemical requirements as well as the various routes for producing transparent photocatalytic and nanoparticle-based UV-blocking coatings and sunscreens. The authors review the main methods for synthesizing titania, zinc oxide and ceria nanoparticles, with a focus on recent research on the generation of non-agglomerated powders. (Agglomeration is often the major cause of poor performance and limited transparency.) The authors also identify organic additives that are efficient dispersants and can improve the compatibility of inorganic nanoparticles with an organic matrix.

In addition to discussing the technical performance of nanoparticles, the authors address concerns related to distributing them in the environment. They conclude by describing future prospects for nanoparticles and identifying promising materials, such as multifunctional coatings and hybrid films.

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The above story is reprinted from materials provided by National Institute for Materials Science, via ResearchSEA.

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Journal Reference:

1. Bertrand Faure, German Salazar-Alvarez, Anwar Ahniyaz, Irune Villaluenga, Gemma Berriozabal, Yolanda R De Miguel, Lennart Bergstr?m. Dispersion and surface functionalization of oxide nanoparticles for transparent photocatalytic and UV-protecting coatings and sunscreens. Science and Technology of Advanced Materials, 2013; 14 (2): 023001 DOI: 10.1088/1468-6996/14/2/023001

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/5iewoNBStdY/130428144955.htm

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Israel lawmaker claims Hezbollah getting chemicals from Syria

JERUSALEM (AP) ? A former Israeli defense minister alleged Monday that Syria's chemical weapons are "trickling" to the Lebanese militant group Hezbollah, the first claim by a senior politician in Israel that one of the country's nightmare scenarios is coming true.

Binyamin Ben-Eliezer, who also called for international intervention in the Syria's civil war to stop mass civilian deaths, did not supply any evidence for his claim.

"The process of weapon transferal to Hezbollah has begun," Ben-Eliezer told The Associated Press. He refused to elaborate.

Ben-Eliezer, a retired general who is now a lawmaker from the opposition Labor party, also told Israel Radio that he "has no doubt" that Syrian President Bashar Assad has already used chemical weapons and that that "these weapons are trickling to Hezbollah."

His statements do not represent an official assessment and defense officials say that, while they are concerned about Hezbollah getting chemical weapons, they are assuming it has not yet done so.

Israel has repeatedly expressed concern that Syria's chemical arsenal could fall into the hands of anti-Israel militants like Lebanon's Hezbollah, an Assad ally, or an al-Qaida-linked group fighting with the rebels. Prime Minister Benjamin Netanyahu has warned that militants getting chemical arms or other sophisticated weapons is a red line that could trigger military action.

Israel is widely believed to have carried out an airstrike in Syria early this year on a shipment of sophisticated anti-aircraft missiles allegedly bound for Hezbollah. Israel has all but confirmed it carried out the attack.

Although Assad is a bitter enemy, Israel has been careful not to take sides in Syria's civil war, partly because the Assad family has kept the border with Israel quiet for the past 40 years and because of fears of what would happen if he is overthrown. Israeli military officials believe some Syrian opposition groups, especially those affiliated with the al-Qaida terror group, will turn their focus toward Israel once Assad is ousted.

Ben-Eliezer said he is "amazed by the silence of the world" and that the international community needs to intervene to end the high civilian death toll in Syria's civil war. He said Israel should consider action if there is no international intervention.

"I wouldn't rule out preparing a plan for Israel to act if the world continues to remain silent and the weapons continue to flow to Hezbollah. These are crazy people, terrorists who will not hesitate to use this tomorrow morning," he said.

This week another former defense chief, Environment Minister Amir Peretz, also called for international action in Syria.

Both sides in Syria's civil war accuse each other of using chemical weapons in the war, which according to the U.N. has killed more than 70,000 people.

The U.S. has warned such weapons cross a red line and last week said the weapons were probably used, though it still seeks definitive proof.

Last week, Brig. Gen. Itai Brun, the head of research and analysis in Israeli military intelligence, said Assad's soldiers had used chemical weapons against rebels. He said sarin, a lethal nerve agent, was probably used in one instance. He cited images of alleged victims of the attacks foaming at the mouth and displaying other apparent symptoms of chemical attacks as part of the evidence.

The Israeli government convened its Security Cabinet to discuss Syria on Sunday but no details were released.

Source: http://news.yahoo.com/israel-lawmaker-claims-hezbollah-getting-chemicals-122131118.html

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Mapping of cancer cell fuel pumps paves the way for new drugs

Apr. 28, 2013 ? For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells. Since tumours are highly dependent on the transportation of nutrients in order to be able to grow rapidly, the researchers are hoping that the study published in the scientific magazine Nature Structural & Molecular Biology will form the basis for new strategies to fight cancer cells.

In order to be able to fuel their rapid growth, cancer tumours depend on transporter proteins to work at high speed to introduce sugars and other nutrients that are required for the cell's metabolism. One possible treatment strategy would therefore be to block some of the transporters in the cell membrane which operate as fuel pumps, thus starving out and killing the cancer cells.

One important group of membrane transporters is the GLUT family, which introduces glucose and other sugars into the cell. Glucose is one of the most important energy sources for cancer cells and GLUT transporters have been shown to play a key role in tumour growth in many different types of cancer.

In the current study, researchers from Karolinska Institutet have performed a detailed study of the way in which suger transport is executed by the protein XylE, from the Escherichia colibacterium, whose function and structure is very similar to GLUT transporters in humans. For the first time, the researchers have described the way in which the protein's structure changes between two different conformations when it binds and transports a sugar molecule.

"In showing details of the molecular structure of the region that bind the sugar, our study opens up the opportunities to more efficiently develop new substances that may inhibit GLUT transporters," says P?r Nordlund at the Department of Medical Biochemistry and Biophysics, one of the researchers behind the study. "Information on the structure of the transport protein facilitates the development of better drugs in a shorter time. Such GLUT inhibitors could potentially be used to treat cancer in the future."

The study may be of significance not just to cancer research but also in the field of diabetes. GLUT plays a key role in diabetes since insulin works by activating the uptake of glucose from the blood by means of GLUT transporters in the cell membrane.

GLUT and the studied XylE transporter belong to the very large group of metabolite transporters called the Major Facilitator Superfamily (MFS), which is important in many diseases and for the uptake of medicines in cells.

"Many aspects concerning molecular mechanisms for the function of GLUT transporters are probably common to many members of the MFS family, which are involved in a broad spectrum of diseases in addition to cancer and diabetes," says P?r Nordlund.

As well as membrane transporters, which have undergone in-depth analysis in the current study, many different membrane proteins pass through the surface membrane of the cells. Their significance to the cell function and the development of drugs has been noted before, not least through the Nobel Prizes that were awarded to researchers who used mechanistic and structural studies to map the function of two other major membrane protein families, G-protein-coupled receptors and ion channels.

The current study has been financed by grants from the Swedish Research Council, the Swedish Cancer Society, the European Molecular Biology Organization (EMBO) and The Danish Council for Independent Research.

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Journal Reference:

1. Esben M Quistgaard, Christian L?w, Per Moberg, Lionel Tr?saugues, P?r Nordlund. Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters. Nature Structural & Molecular Biology, 2013; DOI: 10.1038/nsmb.2569

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/YpfcBJy_z0w/130428144853.htm

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European markets outperform on ECB rate cut hopes

LONDON (AP) ? The positive tone in markets continued Wednesday, particularly in Europe, as investors grew more hopeful of an interest rate cut from the European Central Bank. Weak U.S. economic data weighed on U.S. shares, however, despite more upbeat earnings.

In Europe, investors were further buoyed by mounting expectations of a rate cut next week from the ECB after another weak business survey for Germany, Europe's biggest economy. The Ifo Institute said its main index of business optimism fell to 104.4 points from 106.7 in March. Market analysts had expected a more modest decline to 106.2.

"With talk of a rate cut in recent policy meetings and the latest soft data, the ECB may finally be ready to make one final conventional move," said Benjamin Reitzes, an analyst at BMO Capital Markets.

In Europe, Germany's DAX rose 1 percent to 7,737 while the CAC-40 in France was 1.2 percent higher at 3,828. Meanwhile, the FTSE 100 index of leading British shares was up 0.4 percent at 6,434 ? Britain doesn't use the euro so it isn't directly affected by developments with regard to the ECB, which controls monetary policy for the 17 European Union countries that use the euro.

European markets have also been buoyed in recent days by progress in Italy to produce a government after inconclusive elections in February.

Italy's president appointed Enrico Letta as premier-designate Wednesday, asking him to form a coalition government and end two months of political paralysis to put the country back on the path of reform and growth. Letta, a 46-year-old longtime center-left lawmaker and No. 2 Democratic Party leader, said he accepted the job knowing it's an enormous responsibility and that Italy's political class "has lost all credibility."

In the U.S., disappointing durable goods order figures dampened down the spirits in the markets despite upbeat earnings statements from the likes of Apple and Sprint Nextel. Procter & Gamble disappointed with a revenue miss.

The Commerce Department reported that durable goods declined 5.7 percent in March largely on the back of lower aircraft bookings. The fall, which was larger than anticipated, followed a 4.3 percent gain the previous month.

"The report will not remove growing concerns that the economy is facing a now typical slowdown," said Andrew Wilkinson, chief economic strategist at Miller Tabak & Co.

Earlier in Asia, stocks rallied in the wake of the big gains recorded in Europe and the U.S. the previous day. Japan's Nikkei 225 index jumped 2.3 percent to close at 13,843.46, its highest close since June 2008, while South Korea's Kospi rose 0.9 percent to 1,935.31.

Hong Kong and mainland Chinese stocks also climbed on expectations that the central government might take action to boost the Chinese economy after recent data showed growth lagging in the world's No. 2 economy.

Hong Kong's Hang Seng advanced 1.7 percent to 22,183.05. Mainland Chinese shares bounced back a day after sharp drops. The Shanghai Composite Index rose 1.6 percent to 2,218.32 and the Shenzhen Composite Index gained 2.2 percent to 943.78.

The currency markets were relatively subdued, with the euro 0.1 percent lower at $1.2990 and the dollar steady at 99.45 yen.

Oil prices advanced, with the benchmark New York rate up 62 cents at $89.80 a barrel.

Source: http://news.yahoo.com/european-markets-outperform-ecb-rate-cut-hopes-141716151--finance.html

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Dropcam software for iOS updated with location and time-based triggers

Dropcam, an iOS-friendly Wi-Fi-enabled camera system, recently updated their iPhone and iPad apps so that recording can kick in when you leave the house or at certain times of the day. As always, the Dropcam can push alerts to your iPhone or iPad when the camera detects movement and, if you're a subscriber, let you comb through up to 30 days of previously stored footage, complete with movement markers along the timeline and audio.

Of course, the primary use case for this kind of thing is for home security, but you can also open up the live stream publicly, which is great if you've got an ongoing event that you'd like to share with the world. The only major downside to the camera itself is that it's got to be plugged in all the time, but for a home security system, that shouldn't be much of a problem.

I'm finding myself more and more interested in connected home gadgets like Dropcam, Lockitron, and Lifx. Dropcam in particular seems like it's really easy to set up, and pretty useful, but what do you guys think? What kind of home security do you use? Is it hooked up to your iPhone in any way?

• Free - Download Now

Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/hkwB5V3LLos/story01.htm

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Insert Coin: Snapzoom gives Kickstarters a crack at its smartphone scope adapter (video)

In Insert Coin, we look at an exciting new tech project that requires funding before it can hit production. If you'd like to pitch a project, please send us a tip with "Insert Coin" as the subject line.

Snapzoom stole a lot of hearts at Engadget Expand, but it didn't quite steal enough votes to win our Insert Coin contest. Now you can exact some justice, as the smartphone adapter for binoculars, telescopes and microscopes is up for grabs on Kickstarter to let you zoom in on the moon, bacteria or whatever else you can think of. So far it's vacuumed up $15,000 toward its $55,000 goal, and while the early bird offer is sold out, backers can still grab one starting at $60, a hefty discount from the final $80 retail price. For $90, you'll even get a basic 10x25 compact Bushnell travel binocular tossed in, so if you want to see what made our Insert Coin judges go zoom-crazy, hit the source or video after the jump.

Filed under: Cellphones, Cameras

Comments

Source: Snapzoom (Kickstarter)

Source: http://www.engadget.com/2013/04/25/insert-coin-snapzoom-on-kickstarter/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Infants' sweat response predicts aggressive behavior as toddlers

Apr. 23, 2013 ? Infants who sweat less in response to scary situations at age 1 show more physical and verbal aggression at age 3, according to new research published in Psychological Science, a journal of the Association for Psychological Science.

Lower levels of sweat, as measured by skin conductance activity (SCA), have been linked with conduct disorder and aggressive behavior in children and adolescents. Researchers hypothesize that aggressive children may not experience as strong of an emotional response to fearful situations as their less aggressive peers do; because they have a weaker fear response, they are more likely to engage in antisocial behavior.

Psychological scientist Stephanie van Goozen of Cardiff University and colleagues wanted to know whether the link between low SCA and aggressive behaviors could be observed even as early as infancy.

To investigate this, the researchers attached recording electrodes to infants' feet at age 1 and measured their skin conductance at rest, in response to loud noises, and after encountering a scary remote-controlled robot. They also collected data on their aggressive behaviors at age 3, as rated by the infants' mothers.

The results revealed that 1 year-old infants with lower SCA at rest and during the robot encounter were more physically and verbally aggressive at age 3.

Interestingly, SCA was the only factor in the study that predicted later aggression. The other measures taken at infancy -- mothers' reports of their infants' temperament, for instance -- did not predict aggression two years later.

These findings suggest that while a physiological measure (SCA) taken in infancy predicts aggression, mothers' observations do not.

"This runs counter to what many developmental psychologists would expect, namely that a mother is the best source of information about her child," van Goozen notes.

At the same time, this research has important implications for intervention strategies:

"These findings show that it is possible to identify at-risk children long before problematic behavior is readily observable," van Goozen concludes. "Identifying precursors of disorder in the context of typical development can inform the implementation of effective prevention programs and ultimately reduce the psychological and economic costs of antisocial behavior to society."

Co-authors on this research include Erika Baker, Katherine Shelton, Eugenia Baibazarova, and Dale Hay of Cardiff University.

This research was supported by studentships from the School of Psychology, Cardiff University, and by a grant from the Medical Research Council.

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Journal Reference:

1. E. Baker, K. H. Shelton, E. Baibazarova, D. F. Hay, S. H. M. van Goozen. Low Skin Conductance Activity in Infancy Predicts Aggression in Toddlers 2 Years Later. Psychological Science, 2013; DOI: 10.1177/0956797612465198

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/RDqcrJSHhhk/130423135714.htm

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These Super-Sleek Headphones Are Inspired By High-End HiFi

KEF is one of those companies that quietly gets one with making amazing—and expensive—HiFi equipment. Now, however, it's decided to apply its knowledge of HiFi and branch out into headphones—and these things promise to be amazing. More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/50NbdUKLPPY/these-super+sleek-headphones-are-inspired-by-high+end-hifi

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Workplace stress poses risk to health

Apr. 23, 2013 ? Stressful situations at work can have a negative impact on the cardiovascular system and the metabolism. Stress, which is transmitted by direct and indirect signaling pathways, leads to an inflammatory response in the body, which can trigger cardiovascular diseases, amongst others.

These results, which were achieved by scientists from the Helmholtz Zentrum M?nchen following their evaluation of data from a population-based cohort study, were published in the specialist journals Brain, Behavior, and Immunity and Psychosomatic Medicine.

The study is based on a long-term observation of more than 950 people as part of the population-based cohort study MONICA/KORA. The work was conducted by Dr. Rebecca Emeny as part of the Mental Health working group headed by Prof. Karl-Heinz Ladwig, Institute of Epidemiology II (EPI II) at the Helmholtz Zentrum M?nchen (HMGU). Data was analyzed from questionnaires on psychological stress at work and concentrations of inflammatory biomarkers in the blood. The results showed that healthy workers who were exposed to stress at work displayed significantly elevated inflammatory parameters and faced twice the risk of cardiovascular diseases.

More than half of the participants in the study stated that they experienced psychological strain and stress at work. Stress is regarded as a cardiovascular risk factor. Its consequences are communicated directly via activated messenger substances as well as indirectly via unhealthy stress-related behavior. In particular, the scientists found a clear association between stress and elevated concentrations of CRP (C-reactive protein), which is an inflammatory marker, and were thus able to demonstrate a stress-related inflammatory reaction in the body. Moreover, job stress led to harmful psychological effects such as depression and sleep disturbances as well as to unhealthy behavior, for example, physical inactivity. Doing sports regularly, for at least one hour per week, significantly reduced inflammatory activity. However, the differences in terms of health risks between people who suffered from work stress and those who did not still remained.

With their analysis, the scientists at HMGU have made a substantial contribution towards a deeper understanding of stress-related responses in the body. "The insights gained from this study form important starting points for finding preventive measures that will protect against stress-related diseases such as coronary heart disease," says Dr. Emeny, first author of the study.

Environmental factors and lifestyle play a major role in the development of common diseases in Germany such as cardiovascular diseases and diabetes mellitus. The aim of the Helmholtz Zentrum M?nchen is to develop new approaches for the diagnosis, therapy and prevention of the most common diseases.

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Journal References:

1. Rebecca Emeny, Marie-Elena Lacruz, Jens Baumert, Astrid Zierer, Alexander von Eisenhart Rothe, Christine Autenrieth, Christian Herder, Wolfgang Koenig, Barbara Thorand, Karl-Heinz Ladwig. Job strain associated CRP is mediated by leisure time physical activity: Results from the MONICA/KORA study. Brain, Behavior, and Immunity, 2012; 26 (7): 1077 DOI: 10.1016/j.bbi.2012.07.004
2. Emeny, R.T. et al. Contributions of Job Strain and 9 Emerging Biomarkers of Coronary Events in Healthy Workers: the MONICA/KORA Augsburg Case-Cohort. Psychosomatic Medicine, 75(3):317-25

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/mind_brain/mental_health/~3/uVpg6C8YPCY/130423090940.htm

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The Importance of Relationship Building: Negotiating in China | The ...

As a general rule, when you are dealing with Chinese business people it is best to hire someone with some sort of ties to them so that you can gain some leverage into their social network. A large part of the Chinese society is centered around guanxi, which is the concept of building personal relationship with people that you can give and receive special favors from. As an outsider you are immediately at a disadvantage unless you can increase the level of trust which is ultimately at the heart of this issue.

Cultivating guanxi with your potential business partners in China can be helped along by hiring people that are already close to them as part of your team, or by developing relationships with some of their key contacts. This is not uncommon to the way that business is conducted throughout the world but in China the intensity of this practice is greater. The sense of guanxi is a powerful tool that you can leverage by spending time cultivating the key relationships with all of the business people that you need to know.

The normal business practices aside, the Chinese will trust you more once you have cultivated the relationship with them rather than just signing a binding contract. This method continues due to the fact that China?s legal system in underdeveloped and under-enforced. Once you have gained the trust through guanxi your business interactions will become a lot easier as they will go above and beyond to help you and your business. Don?t forget that they will also expect something in return for any favors that they provide for you.

Just as the trust of a handshake has been replaced with a mountain of paperwork in the western business world, China?s legal system is improving. But the speed at which they are improving will leave plenty of time for the concept of guanxi to infiltrate another generation or two. Until the legal reform makes this kind of inner circle business relationships more flexible and open, you have to play by the rules that are dictated. Trust is the lynch pin that can expedite and alleviate all of your business transactions throughout the world, but in China you need to manage your network and ensure that you have multiple guanxi links to your business partners to maintain a close bond. Keep in mind that any favors that you receive, even if you didn?t ask for them, have to be reciprocated to maintain the relationships.

What are you think about it? Please ?leave a response in comment?.

You can leave a response, or trackback from your own site.

Source: http://china-business-connect.com/the-importance-of-relationship-building-negotiating-in-china.htm

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Suze Orman teaching personal finance class -- at the University of ...

Sorry, Readability was unable to parse this page for content.

Source: http://www.ecampusnews.com/around-the-web/suze-orman-teaching-personal-finance-class-at-the-university-of-phoenix/

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Obama to host women of the Senate for dinner on Tuesday

WASHINGTON (Reuters) - President Barack Obama has invited the 20 women elected to the U.S. Senate for dinner at the White House on Tuesday, another chapter in his effort to develop closer ties with Congress.

Since March, Obama has taken pains to reach out to lawmakers, trying to find common ground to end a two-year fight over federal deficits, and moving forward on top legislative priorities such as immigration reform.

Obama has held two dinners with small groups of Republican senators and one with Democratic senators.

He also traveled to Capitol Hill in March to meet with Democratic and Republican caucuses in both the House of Representatives and the Senate.

Tuesday's dinner will be the first bipartisan get-together. The White House did not give details on how many senators would attend.

Senator Kirsten Gillibrand, a New York Democrat, said on Twitter that Obama had invited all women in the Senate. Senator Kelly Ayotte, a New Hampshire Republican, confirmed the bipartisan invitation to Reuters.

November's election resulted in a record number of women in the Senate - a total of 16 Democrats and four Republicans.

(Reporting by Roberta Rampton, Richard Cowan and Patricia Zengerle; Editing by Vicki Allen)

Source: http://news.yahoo.com/obama-host-women-senate-dinner-tuesday-231000020--business.html

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Boston Bombing Suspects Acted Alone? - Business Insider

The mayor of Boston says it c appears the two suspects in Monday's Boston Marathon bombing acted alone.

"All of the information that I have they acted alone," Thomas Menino said during an appearance on ABC's "This Week with George Stephanopoulos" Sunday.

However, he added that it was not clear if they would be able to question the suspects about the possibility of outside help.

"The older brother's dead now. We have the second one at Beth Israel Hospital in very serious condition," he said "And we don't know if we'll ever be able to question the individual."

So far the FBI has only named two people in relation to the attack. Both suspects,?Dzhokhar and Tamerlan Tsarnaev, had family ties to Chechnya, an area of Russia known for Islamic insurgency. The older suspect, Tamerlan, took a six-month-long trip to nearby Dagestan last year that is being investigated.

However, no other groups or individuals have been linked to Monday's bombing. A website affiliated with rebels from the North Caucasus region has disavowed the attack with a note saying "Caucasus fighters are not waging any military activities against the United States of America."

Menino said that another individual was taken into custody after the discovery of a pipe bomb, but this was not related to Monday's bombing.

Source: http://www.businessinsider.com/boston-bombing-suspects-acted-alone-2013-4

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Jonas Brothers Glad 'People Are Actually Showing Up' After Reunion

After three-year hiatus, the JoBros tell MTV News they've made their 'best record yet.'
By Jocelyn Vena, with reporting by Christina Garibaldi

Jonas Brothers: Live From MTV
Photo: MTV News

Source: http://www.mtv.com/news/articles/1706095/jonas-brothers-reunion-success.jhtml

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These old AT&T commercials were a pretty good glimpse of today's tech

What was science fiction in 1993 has turned into just science in 2013

Long before you did all these things with that tiny device you're holding in your hands, AT&T commercials from the early 1990s told the future. Navigation, PayPass systems, video conferencing and more have all turned from twentieth-century fantasy into twenty-first century reality.

Or maybe Elias is right, and Tom Selleck is a Timelord. Either way they're worth a look.

Via: +Elias Lugo

Source: http://feedproxy.google.com/~r/androidcentral/~3/K2N5mNkmHgc/story01.htm

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China criticizes US for its human rights record

BEIJING (AP) ? China slammed the human rights record of the United States in response to Washington's report on rights around the world, saying that U.S. military operations have infringed on rights abroad and that political donations at home have thwarted the country's democracy.

The report released Sunday in China ? which defines human rights primarily in terms of improving living conditions for its 1.3 billion people? also cited gun violence in the U.S. among its examples of human rights violations, saying it was a serious threat to the lives and safety of America's citizens.

The Human Rights Record of the United States in 2012 said the U.S. government continues to strengthen the monitoring of its people and that political donations to election campaigns have undue influence on U.S. policy.

"American citizens do not enjoy a genuinely equal right to vote," the report said, citing a decreased turnout in the 2012 presidential election and a voting rate of 57.5 percent.

The report from the information office of the State Council, or China's Cabinet, which mostly cited media reports, said there was serious sex, racial and religious discrimination in the U.S. and that the country had seriously infringed on the human rights of other nations through its military operations in Afghanistan, Pakistan and Yemen.

The U.S.'s annual global human rights report issued Friday by the State Department said China had imposed new registration requirements to prevent groups from emerging that might challenge government authority. It said Chinese government efforts to silence and intimidate political activists and public interest lawyers continued to increase, and that authorities use extralegal measures such as enforced disappearance to prevent the public voicing of independent opinions.

It also said there was discrimination against women, minorities and people with disabilities, and people trafficking, the use of forced labor, forced sterilization and widespread corruption.

China's authoritarian government maintains strict controls over free speech, religion and political activity ? restrictions that the U.S. considers human rights violations.

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Online: Report (in Chinese): http://bit.ly/17b8hnh

Source: http://news.yahoo.com/china-criticizes-us-human-rights-record-054853559.html

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Maduro to be sworn in as Venezuela reviews disputed vote

By Daniel Wallis and Brian Ellsworth

CARACAS (Reuters) - Nicolas Maduro will be sworn in as Venezuela's president on Friday at a ceremony attended by several Latin American leaders, after a decision to widen an electronic audit of the vote took some of the heat out of a dispute over his election.

Maduro, a former bus driver-turned-foreign minister who became the late Hugo Chavez's chosen successor, narrowly beat opposition challenger Henrique Capriles in Sunday's vote.

He accused Capriles of triggering post-election violence that killed eight people, though the opposition says Maduro allies staged some incidents to distract from the vote dispute.

"We have stopped a coup in its first stage. They are beaten, but they are coming back with a new attack," Maduro said on Thursday before flying to Peru for a last-minute meeting of South American leaders to discuss the situation.

While he was in Lima, Venezuela's electoral authority said it would widen to 100 percent an audit of electronic votes from a previous audit that reviewed 54 percent.

"We do this in order to preserve a climate of harmony ... and isolate violent sectors that are seeking to injure democracy," Tibisay Lucena, president of the National Electoral Council (CNE), said in a televised speech to the nation.

Maduro, 50, received a show of support at the late-night meeting of a group of South American nations called Unasur, which welcomed the CNE's move, congratulated him on his victory, and called on both sides to reject violence.

Capriles, who insists the opposition's figures show he won, said he accepted the CNE's decision although it fell short of the manual recount he had wanted. He said he was sure the truth would come out.

The date for the start of the wider audit is to be announced by next week.

Heads of state who will join Maduro's swearing-in include Brazil's Dilma Rousseff and Iran's Mahmoud Ahmadinejad, along with leaders of Chavez-era allies such as Bolivia, Uruguay and Nicaragua.

Russia and China, both partners in major oil projects in Venezuela's vast Orinoco belt region, sent delegations headed by senior officials.

MILITARY PARADE

The inauguration ceremony is due to be held at the National Assembly and will be followed by a military parade. Jets making practice runs have often soared over the capital this week.

Argentine President Cristina Fernandez said on Twitter that on Saturday morning she planned to visit the military museum in Caracas where her friend Chavez is buried.

"I want to be there a bit more alone, without so many people, without so much noise," she said. "To Caracas, without Hugo. It's going to be difficult and strange at the same time. His funerals were so impressive it was like I was in a daze."

The unrest in Venezuela, just weeks after Chavez's death from cancer, has exposed the deep polarization of a country split down the middle between pro- and anti-government factions.

Maduro's administration accuses "fascist" Capriles supporters of going on the rampage, shooting people, attacking offices belonging to the ruling Socialist Party, and setting fire to government-run clinics staffed by Cuban doctors.

Capriles, who has repeatedly called on his supporters to behave peacefully, has said the government was to blame for any violence because of its refusal to hold a recount.

"We have identified where the problems are. With this, we're where we want to be," he said of the vote audit. He also demanded the government stop "persecuting" his supporters, and said there was no evidence of attacks on the state-run clinic, known as CDIs.

"I asked for reports from all the country's municipalities about incidents at CDIs," he said on Twitter. "None were affected. Only sick minds would do something like this!"

(Editing by Philip Barbara)

Source: http://news.yahoo.com/maduro-looks-south-american-backing-venezuela-dispute-032308705.html

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Routine EKG finding could signal serious heart problem

Apr. 16, 2013 ? A common test that records the heart's electrical activity could predict potentially serious cardiovascular illness, according to a UC San Francisco-led study.

A cardiac condition called left anterior fascicular block (LAFB), in which scarring occurs in a section of the left ventricle, may not be as benign as currently thought and could increase the likelihood of heart failure, sudden cardiac death or atrial fibrillation.

In a study to be published on April 17 in the Journal of the American Medical Association (JAMA), UCSF researchers and their colleagues at Wake Forest School of Medicine and the University of Washington, Seattle, analyzed data on 1,664 people over the age of 65 who were medically followed for 16 years.

The researchers selected those who had no evidence of cardiovascular disease from the National Institutes of Health-sponsored Cardiovascular Health Study. People with heart failure, high blood pressure or diabetes, or who had heart attacks, were excluded from the study sample.

"We then compared those with LAFB to those with a normal electrocardiogram (EKG)," said senior author Gregory Marcus, MD, an electrophysiologist with the UCSF Division of Cardiology and an associate professor in residence with the UCSF School of Medicine. "We found that those who had LAFB indeed had a higher risk of atrial fibrillation, congestive heart failure and death."

After adjusting for other potential confounding variables, LAFB posed a 57 percent greater risk for sudden cardiac death, an 89 percent greater risk for atrial fibrillation, and a 143 percent greater risk for heart failure.

LAFB is a blockage of one of the electrical branches that delivers electrical signals to a part of the left ventricle, one of two chambers in the heart. Small studies suggest it is associated with fibrosis or scarring of the left ventricle, but the clinical ramifications of this have not been previously studied. It is unknown how many people LAFD affects.

"We now have come to realize that important cardiovascular diseases like atrial fibrillation, heart failure and maybe sudden cardiac death, are related to fibrosis of the left side of the heart," said Marcus, who sees cardiology patients at the UCSF Medical Center. "So we sought to test the hypothesis that LAFB, even in those people who are otherwise healthy, might be a readily available marker that any doctor can see on an EKG, of a propensity to left-heart fibrosis. And it therefore might predict those at risk for atrial fibrillation, heart failure and death."

There currently is no treatment for people with LAFB. However, this new finding potentially could open up a new area of research in cardiology, according to Marcus.

"Currently there is a therapy for people with heart failure and a left bundle branch block using a special pacemaker called a biventricular pacemaker or cardiac resynchronization therapy," Marcus said. "So one question we have to explore is whether people with LAFB and heart failure, for example, might benefit from a specialized pacemaker."

Patients also can reduce their overall cardiovascular risk with lifestyle modifications, which include choosing a healthy diet, exercising regularly and eliminating tobacco products.

"This study may suggest that LAFB, even in the absence of known high blood pressure or diabetes, should be thought of as a cardiovascular risk factor," Marcus said. "Those patients with LAFB perhaps should be considered the same as someone with an established cardiovascular risk factors."

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The above story is reprinted from materials provided by University of California - San Francisco. The original article was written by Leland Kim.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/AutssVuRlOY/130416161831.htm

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Recipe for large numbers of stem cells requires only one ingredient

Apr. 17, 2013 ? Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the National Institutes of Health (NIH). Their experiments, reported today in Scientific Reports, also show that the process doesn't require other kinds of cells or agents to artificially support cell growth and doesn't activate cancer genes.

Scientists hope lab-grown stem cells and induced pluripotent stem (iPS) cells, which have the ability to produce specialized cells such as neurons and cardiac cells, could one day be used to treat diseases and repair damaged tissues, said co-author Jeffrey S. Isenberg, M.D., associate professor, Division of Pulmonary, Allergy and Critical Care Medicine, Pitt School of Medicine.

"Even though stem cells are able to self-renew, they are quite challenging to grow in the lab," he said. "Often you have to use feeder cells or introduce viral vectors to artificially create the conditions needed for these cells to survive and thrive."

In 2008, prior to joining Pitt, Dr. Isenberg was working in the National Cancer Institute (NCI) lab of senior author David D. Roberts, Ph.D., using agents that block a membrane protein called CD47 to explore their effects on blood vessels. He noticed that when cells from the lining of the lungs, called endothelium, had been treated with a CD47 blocker, they stayed healthy and maintained their growth and function for months.

Dr. Roberts' NIH team continued to experiment with CD47 blockade, focusing on defining the underlying molecular mechanisms that control cell growth.

They found that endothelial cells obtained from mice lacking CD47 multiplied readily and thrived in a culture dish, unlike those from control mice. Lead author Sukhbir Kaur, Ph.D., discovered that this resulted from increased expression of four genes that are regarded to be essential for formation of iPS cells. When placed into a defined growth medium, cells lacking CD47 spontaneously formed clusters characteristic of iPS cells. By then introducing various growth factors into the culture medium, these cells could be directed to become cells of other tissue types. Despite their vigorous growth, they didn't form tumors when injected into mice, a major disadvantage when using existing iPS cells.

"Stem cells prepared by this new procedure should be much safer to use in patients," Dr. Roberts noted. "Also, the technique opens up opportunities to treat various illnesses by injecting a drug that stimulates patients to make more of their own stem cells."

According to Dr. Isenberg, "These experiments indicate that we can take a primary human or other mammalian cell, even a mature adult cell, and by targeting CD47 turn on its pluripotent capability. We can get brain cells, liver cells, muscle cells and more. In the short term, they could be a boon for a variety of research questions in the lab."

In the future, blocking CD47 might make it possible to generate large numbers of healthy cells for therapies, such as alternatives to conventional bone marrow transplantation and complex tissue and organ bioengineering, he added.

"These exciting findings provide a rationale for using CD47 blocking therapies to increase stem cell uptake and survival in transplanted organs, matrix grafts, or other applications," said Mark Gladwin, M.D., professor and chief, Division of Pulmonary, Allergy and Critical Care Medicine, Pitt School of Medicine. "This continues a strong and productive collaboration between investigators at the NCI and the University of Pittsburgh's Vascular Medicine Institute."

Co-authors of the paper include David R. Soto-Pantoja, Ph.D., Michael L. Pendrak, Ph.D., Alina Nicolae, M.D., Ph.D., Zuqin Nie, Ph.D., and David Levens, M.D., Ph.D., of the National Cancer Institute (NCI); Erica V. Stein, B.S., M.Ed., of NCI and George Washington University; Chengyu Liu, Ph.D., of the National Heart, Lung and Blood Institute; Abdel G. Elkahloun, Ph.D., of the National Human Genome Research Institute (NHGRI); and Satya P. Singh, Ph.D., of the National Institute of Allergy and Infectious Diseases.

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The above story is reprinted from materials provided by University of Pittsburgh Schools of the Health Sciences.

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Journal Reference:

1. Sukhbir Kaur, David R. Soto-Pantoja, Erica V. Stein, Chengyu Liu, Abdel G. Elkahloun, Michael L. Pendrak, Alina Nicolae, Satya P. Singh, Zuqin Nie, David Levens, Jeffrey S. Isenberg, David D. Roberts. Thrombospondin-1 Signaling through CD47 Inhibits Self-renewal by Regulating c-Myc and Other Stem Cell Transcription Factors. Scientific Reports, 2013; 3 DOI: 10.1038/srep01673

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/2U0OelYpsXM/130417092134.htm

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NKorea, marking leader's birthday, shows more ire

PYONGYANG, North Korea (AP) ? After a day of festivities to mark the 101st birthday of its first leader, North Korea on Tuesday offered new prickly rhetoric against the United States and South Korea, which are watching closely for signs whether it will conduct a medium-range missile test in defiance of international concerns.

State media said the Supreme Command of the Korean People's Army issued an ultimatum demanding an apology from South Korea for "hostile acts" and threatening that unspecified retaliatory actions would happen at any time.

The statement, relayed through the KCNA state media agency, came after a day of festivities in North Korea's capital that featured art performances, public dances and crowds thronging to giant bronze statues to pay homage to the late leader Kim Il Sung,

The renewed rhetoric was sparked by a protest in downtown Seoul, where effigies of Kim Il Sung and his son and successor, late leader Kim Jong Il, were burned. Such protests are not unusual in South Korea and this one likely gave the North a pretext to react negatively to calls for joining in dialogue with its neighbors than an actual cause for retaliation.

The North's statement said it would refuse any offers of talks with the South until it apologized for the "monstrous criminal act." North Korea often denounces such protests, but rarely in the name of the Supreme Command, which is headed by Kim Il Sung's grandson and North Korea's new leader, Kim Jong Un.

"If the puppet authorities truly want dialogue and negotiations, they should apologize for all anti-DPRK hostile acts, big and small, and show the compatriots their will to stop all these acts in practice," the statement said, referring to North Korea's official name.

South Korea's Defense Ministry said Tuesday it had received no such ultimatum officially, noting that there is no communications line between the two Koreas.

Pyongyang launched a rocket ahead of the last anniversary of Kim Il Sung's birth, which was the centennial, but the holiday this year has been much more low-key, with Pyongyang residents gathering in performance halls and plazas and taking advantage of subsidized treats, like shaved ice and peanuts, despite unseasonably cold weather.

The calm in Pyongyang has been a striking contrast to the steady flow of retaliatory threats North Korea has issued over ongoing military exercises between South Korea and the United States. Though the maneuvers, called Foal Eagle, are held regularly, North Korea was particularly angry over their inclusion this year of nuclear-capable B-2 stealth bombers and F-22 fighters.

"The ultimatum is just North Korea's way of saying that it's not willing or ready to talk with the South," said Chang Yong-seok at the Institute for Peace and Unification Studies at Seoul National University. "North Korea apparently wants to keep the cross-border relations tense for some time to come."

The Tuesday ultimatum comes just after U.S. Secretary of State John Kerry wrapped up a tour to coordinate Washington's response with Beijing, North Korea's most important ally, as well as with Seoul and Tokyo. Kerry said a missile test would be provocation that would further isolate the country and its impoverished people. He said Sunday that the U.S. was "prepared to reach out," but that Pyongyang must first bring down tensions and honor previous agreements.

South Korean Defense Minister Kim Kwan-jin told a parliamentary committee Monday that North Korea still appeared poised to launch a missile from its east coast. North Korea, which conducted a nuclear test in February, has already been slapped with strengthened U.N. sanctions for violating Security Council resolutions barring the regime from nuclear and missile activity.

To further coordinate their response, South Korea's new president, Park Geun-hye, will meet with President Barack Obama on May 7 at the White House.

State Department spokesman Patrick Ventrell said Monday the United States is open to dialogue with North Korea but only if Pyongyang proves itself to be trustworthy.

"The burden remains on Pyongyang. They need to take meaningful steps to show that they'll honor their commitments," Ventrell told reporters in Washington. "We need to see them be serious about denuclearization, indicate their seriousness, and start to reduce the threats and stop provocations."

North Korea has warned that the situation has grown so tense it cannot guarantee the safety of foreigners in the country and said embassies in Pyongyang should think about their evacuation plans. But British Foreign Secretary William Hague said Monday that although there is reason for concern over the "frenetic and bellicose" rhetoric, Britain believes there has been "no immediate increased risk or danger" to those living in or travelling to North Korea.

Pyongyang's media gave little indication of how high the tensions are.

The front page of the Rodong Sinmun, the Workers' Party newspaper, on Tuesday featured photos of Kim Jong Un at a performance the night before of the Unhasu orchestra, along with his aunt, Kim Kyong Hui, and other top officials. North Korean media also reported that he watched volleyball and basketball games between Kim Il Sung University of Politics and Kim Il Sung Military University.

Starting from early Monday morning, residents dressed in their finest clothing began walking from all parts of Pyongyang to lay flowers and bow before the bronze statues of Kim and his son, late leader Kim Jong Il, as the mournful "Song of Gen. Kim Il Sung" played over and over. Similar statues of the Kims are located in every North Korean province.

___

Associated Press writer Sam Kim contributed to this report from Seoul, South Korea.

Source: http://news.yahoo.com/nkorea-marking-leaders-birthday-shows-more-ire-052153500.html

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Engineers craft new material for high-performing 'supercapacitors

Apr. 15, 2013 ? Taking a significant step toward improving the power delivery of systems ranging from urban electrical grids to regenerative braking in hybrid vehicles, researchers at the UCLA Henry Samueli School of Engineering and Applied Science have synthesized a material that shows high capability for both the rapid storage and release of energy.

In a paper published in the April 14 issue of the journal Nature Materials, a team led by professor of materials science and engineering Bruce Dunn defines the characteristics of a synthesized form of niobium oxide with a great facility for storing energy. The material would be used in a "supercapacitor," a device that combines the high storage capacity of lithium ion batteries and the rapid energy-delivery ability of common capacitors.

UCLA researchers said the development could lead to extremely rapid charging of devices, ranging in applications from mobile electronics to industrial equipment. For example, supercapacitors are currently used in energy-capture systems that help power loading cranes at ports, reducing the use of hydrocarbon fuels such as diesel.

"With this work, we are blurring the lines between what is a battery and what is a supercapacitor," said Veronica Augustyn, a graduate student in materials science at UCLA and lead author of the paper. "The discovery takes the disadvantages of capacitors and the disadvantages of batteries and does away with them."

Batteries effectively store energy but do not deliver power efficiently because the charged carriers, or ions, move slowly through the solid battery material. Capacitors, which store energy at the surface of a material, generally have low storage capabilities.

Researchers on Dunn's team synthesized a type of niobium oxide that demonstrates substantial storage capacity through "intercalation pseudocapacitance," in which ions are deposited into the bulk of the niobium oxide in the same way grains of sand can be deposited between pebbles.

As a result, electrodes as much as 40 microns thick -- about the same width as many commercial battery components -- can quickly store and deliver energy on the same time scales as electrodes more than 100 times thinner.

Dunn emphasizes that although the electrodes are an important first step, "further engineering at the nanoscale and beyond will be necessary to achieve practical devices with high energy density that can charge in under a minute."

Co-authors of the study included Dunn; Sarah Tolbert, a UCLA chemistry and biochemistry professor; Augustyn and fellow UCLA Engineering graduate student Jong Woung Kim; Cornell University professor H?ctor Abru?a; Cornell postgraduate researcher Michael Lowe; Patrice Simon, a professor at the Universit? Paul Sabatier in Toulouse, France; and graduate student J?r?my Come and researcher Pierre-Louis Taberna of the Universit? Paul Sabatier.

The research from the Energy Frontier Research Centers, UCLA-based Molecularly Engineered Energy Materials and Cornell-based Energy Materials Center, was supported by the U.S. Department of Energy Office of Basic Energy; a European Research Council grant supported researh from Universit? Paul Sabatier.

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The above story is reprinted from materials provided by University of California - Los Angeles. The original article was written by Bill Kisliuk.

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Journal Reference:

1. Veronica Augustyn, J?r?my Come, Michael A. Lowe, Jong Woung Kim, Pierre-Louis Taberna, Sarah H. Tolbert, H?ctor D. Abru?a, Patrice Simon, Bruce Dunn. High-rate electrochemical energy storage through Li intercalation pseudocapacitance. Nature Materials, 2013; DOI: 10.1038/nmat3601

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_technology/~3/DOO8AUO1QQo/130415124813.htm

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